(23) VISUOSPATIAL AND SEQUENTIAL MEMORY TASK IN HEALTHY ADULTS
¡¡¡¡¡¡35th Annual Meeting of the Society for Neuroscience, 2005-11
¡¡There were various memory assessment batteries; however, a simplified and
objective one for visuospatial and sequential memory has not been established.
In the present study, we administered a visuospatial and sequential memory
task to 154 healthy adult volunteers (20-79 years old) by using a new developed
computer tool and investigated the aging effect on performance. Results:
Results showed a significant effect on the number of cell division. The
elderly performed worse with the tasks in which the stimuli are apparently
random even though the same number of cell division. Thus, aging decline
in this performance may be related to the decrease not only of memory capacity
but of certain frontal lobe functions such as memory for location and sequence
or ability for detecting the stimuli regularity. On this hypothesis, we
recorded 4 subjects eye movements during task performance by NAC Eye Mark
8 and observed the delay of eye movement in elderly but the precedeence
of eye movement in young on the task in which the stimuli showed a regularity
in a sequence order. In contrast, the performance on MMSE was not associated
with age. This suggests that the present simplified visuospatial and sequential
memory task may detect some functional decline which comes before the overall
congnitive impartment seen on MMSE score.