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(23) VISUOSPATIAL AND SEQUENTIAL MEMORY TASK IN HEALTHY ADULTS
¡¡¡¡¡¡35th Annual Meeting of the Society for Neuroscience, 2005-11

¡¡There were various memory assessment batteries; however, a simplified and objective one for visuospatial and sequential memory has not been established. In the present study, we administered a visuospatial and sequential memory task to 154 healthy adult volunteers (20-79 years old) by using a new developed computer tool and investigated the aging effect on performance. Results: Results showed a significant effect on the number of cell division. The elderly performed worse with the tasks in which the stimuli are apparently random even though the same number of cell division. Thus, aging decline in this performance may be related to the decrease not only of memory capacity but of certain frontal lobe functions such as memory for location and sequence or ability for detecting the stimuli regularity. On this hypothesis, we recorded 4 subjects eye movements during task performance by NAC Eye Mark 8 and observed the delay of eye movement in elderly but the precedeence of eye movement in young on the task in which the stimuli showed a regularity in a sequence order. In contrast, the performance on MMSE was not associated with age. This suggests that the present simplified visuospatial and sequential memory task may detect some functional decline which comes before the overall congnitive impartment seen on MMSE score.

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